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. 2009 Sep 25;5(9):e1000521. doi: 10.1371/journal.pcbi.1000521

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Wang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) The bridgeness of aging genes in every pair of diseases. Here, diseases are ordered by their FER (fold enrichment ratio), and minus 10-based logarithm p-value is showed in the figure where values larger than four set to be four. (B–C) Examples show the important functions of aging genes in connecting diseases. MD means that the genes are involved in multiple gene sets.