. Author manuscript; available in PMC: 2009 Sep 8.

Published in final edited form as: Cell Transplant. 2009;18(3):283–295. doi: 10.3727/096368909788535004

Table 1.

Hemodynamics for 3DFC Patch/Captopril After MI

	MAP (mmHg)	HR (bpm)	LV SP (mmHg)	LVEDP (mmHg)	LV dP/dt (mmHg/s)	PDP (mmHg)	Tau (ms)
Sham (N = 14)	106 ± 5	287 ± 15	124 ± 5	7 ± 1	7360 ± 379	192 ± 18	19.0 ± 1.3
MI (N = 18)	90 ± 2^*	269 ± 13	103 ± 3^*	25 ± 2^*	4542 ± 215^*	126 ± 4	24.2 ± 1.8^*
MI + captopril (N = 11)	72 ± 3^*	283 ± 15	88 ± 3^†^‡	14 ± 2^†	4398 ± 315^*	118 ± 7^*	21.8 ± 1.8^*
MI + 3DFC (viable) (N = 11)	84 ± 3^†	248 ± 10	100 ± 5^*	23 ± 2^*^‡	4242 ± 156^*	146 ± 8^†^§	29.7 ± 3.5^*
MI + 3DFC (nonviable) (N = 12)	88 ± 4^*	270 ± 7	102 ± 4^*	24 ± 2^*	4502 ± 179^*	118 ± 4	26.0 ± 3.0^*
MI + 3DFC (viable) + captopril (N = 8)	83 ± 4^†	265 ± 23	100 ± 6^*	13 ± 3^†	4502 ± 179^*	123 ± 5^§	25.8 ± 2.8^*

Values are mean ± SE. MAP, mean arterial pressure; MI, myocardial infarction; LV, left ventricular; LV EDP, LV end-diastolic pressure; PDP, peak developed pressure; Tau, time constant of LV relaxation; 2DFC, three-dimensional fibroblast construct.

p < 0.05 versus sham.

^†

p < 0.05 versus sham and MI.

^‡

p < 0.05 versus MI + 3DFC/captopril.

^§

p < 0.05 versus sham and MI + 3DFC.