Table 2. List of the membrane protein transporters.
Family | PDB | Chain | Protein name | Fraction of cavity residues (%) | Fold-change (%) | |
IS* | Random | |||||
MFS | 2CFQ | A | Lactose permease | 68.00 | 18.78 | 362.09. |
K+ channel | 1ORQ | C | KvAP voltage-gated K+ Channel | 63.64 | 16.63 | 382.68 |
MFS | 1PW4 | A | Glycerol-3-Phosphate Transporter | 72.00 | 20.88 | 344.83 |
ABC transporter | 3D31 | C | Sulfate/molybdate ABC transporter | 75.00 | 25.48 | 294.35 |
MFS | 2GFP | A | Multidrug drug transporter | 61.90 | 24.80 | 249.60 |
K+ channel | 2R9R | B | Kv1.2 voltage-gated K+ channel | 46.15 | 15.61 | 295.67 |
Bacterial rhodopsin | 1E12 | A | Chloride pump halorhodopsin | 66.67 | 27.22 | 244.93 |
ATPase | 3B8E | A | Na+/K+ ATPase | 71.43 | 30.62 | 233.28 |
Bacterial rhodopsin | 1H2S | A | Sensory rhodopsin 2 | 41.67 | 20.48 | 203.45 |
Bacterial rhodopsin | 2EI4 | A | Archaerhodopsin 2 | 69.23 | 38.37 | 180.43 |
Bacterial rhodopsin | 1C3W | A | Bacteriorhodopsin | 31.25 | 20.79 | 150.31 |
GPCR | 1L9H | A | Rhodopsin | 44.44 | 30.57 | 145.39 |
ATPase | 1WPG | A | P-type Ca2+ ATPase | 54.55 | 36.64 | 148.88 |
ATPase | 3B8C | A | Plasma membrane ATPase | 76.19 | 57.94 | 131.50 |
Bacterial rhodopsin | 1UAZ | A | Archaerhodopsin 1 | 31.25 | 24.38 | 128.18 |
*: The fraction of cavity residues was measured within the 90th percentile of IS.