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. Author manuscript; available in PMC: 2010 Sep 15.
Published in final edited form as: Free Radic Biol Med. 2009 Jun 21;47(6):779–785. doi: 10.1016/j.freeradbiomed.2009.06.020

Figure 6.

Figure 6

Protective effect of Amifostine in mouse small intestine epithelium from radiation-induced apoptosis is less pronounced as compared to pyridoxamine. Ten-week old mice were injected IP with PBS or Amifostine (400 mg/kg) 30 min prior to whole body irradiation with either 4 or 8 Gy. Twelve hours later, proximal jejunum was fixed, sectioned and stained using TUNEL kit. Shown are representative micrographs of TUNEL staining (A, cells with dark brown nuclei) and a bar graph of the average numbers of TUNEL-positive cells per HPF in each treatment group with SEM from three experiments; *, P < 0.05 (B).