Table 2.
Adjusted means and SEs for biomarkers among elderly African Americans in Indianapolis, Indiana, and Yoruba people in Ibadan, Nigeria
| Indianapolis | Ibadan | ||
|---|---|---|---|
| Biomarker | Mean (SE)* | Mean (SE)* | P value |
| Women | |||
| Cholesterol (mg/dL) | 194.72 (2.90) | 182.88 (1.75) | .001 |
| Triglycerides (mg/dL) | 99.77 (2.82) | 94.72 (1.70) | .147 |
| HDL cholesterol (mg/dL) | 56.49 (1.01) | 51.50 (.61) | <.001 |
| LDL cholesterol (mg/dL) | 118.27 (2.45) | 112.43 (1.48) | .055 |
| 8-isoprostane (pg/mL) | 566.35 (118.74) | 1165.3 (66.34) | <.001 |
| CRP (mg/L) | 12.54 (1.50) | 7.28 (.89) | .005 |
| PAI-1 (ng/mL) | 20.45 (2.28) | 40.25 (1.36) | <.001 |
| E-selectin (μg/L) | 40.64 (2.65) | 39.46 (1.60) | .720 |
| Homocysteine (μmol/L) | 16.38 (.45) | 16.74 (.27) | .516 |
| Folate (ng/mL) | 10.02 (.55) | 5.87 (.33) | <.001 |
| Vitamin B12 (pg/mL) | 649.67 (24.10) | 794.27 (14.53) | <.001 |
| Men | |||
| Cholesterol (mg/dL) | 178.83 (3.85) | 162.30 (2.14) | <.001 |
| Triglycerides (mg/dL) | 96.72 (4.25) | 86.15 (2.36) | .038 |
| HDL cholesterol (mg/dL) | 49.75 (1.43) | 46.39 (.80) | .050 |
| LDL cholesterol (mg/dL) | 109.73 (3.18) | 98.67 (1.77) | .004 |
| 8-isoprostane (pg/mL) | 784.75 (189.16) | 1271.7 (100.32) | .029 |
| CRP (mg/L) | 9.88 (2.20) | 9.50 (1.19) | .882 |
| PAI-1 (ng/mL) | 15.48 (3.45) | 41.93 (1.83) | <.001 |
| E-selectin (μg/L) | 43.44 (2.07) | 37.96 (1.15) | .028 |
| Homocysteine (μmol/L) | 17.93 (.81) | 19.84 (.44) | .047 |
| Folate (ng/mL) | 10.32 (.67) | 5.28 (.37) | <.001 |
| Vitamin B12 (pg/ml) | 597.21 (31.06) | 735.92 (17.28) | <.001 |
SE, standard error; HDL, high-density lipoprotein; LDL, low-density lipoprotein; CRP, C-reactive protein; PAI-1, plasminogen activator inhibitor type 1.
*
Means were compared by sites after adjusting for age, BMI, alcohol drinking, and smoking and stratified by sex.