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. Author manuscript; available in PMC: 2009 Sep 8.
Published in final edited form as: Med Hypotheses. 2009 Apr 10;73(2):177–183. doi: 10.1016/j.mehy.2009.01.052

Figure 1.

Figure 1

Proposed calcium ion-dependent molecular mechanisms of FMS. Abbreviations: A, site of action of memantine; B, site of action of pregabalin; NMDAR, N-methyl D-aspartate receptor; OPRM1, mu-opioid receptor; ROS, reactive oxygen species; SP, substance P; VGCC, voltage-gated calcium ion channel.