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Activation of ERK1/2 in renal medulla of Sprague-Dawley rats after 5,14-20-HEDE treatment. A: representative Western blot depicting ERK1/2 activation after 5,14-20-HEDE (HEDE) treatment (30 mg/kg sc). p-ERK1/2, phosphorylated ERK1/2; CONT, control. B: p-ERK1/2 densitometry (n = 4 individual animals). **Significant difference from control (P < 0.01).
