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Cytokine production by PBMC derived from non-polymorphic volunteers stimulated with synthetic hexaacylated vs. pentaacylated lipid A. Cells from two wild-type individuals were stimulated with 0.5, 1 or 5 ng/ml of synthetic hexaacylated (closed bars) or pentaacylated (open bars) lipid A and supernatants collected for cytokine determinations as described in Materials and Methods. Results are shown as mean pg/ml ± SD for both volunteers.
