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Electrostatic interactions of LPLA2 with a lipid membrane. -, +, and CAD indicate a negative charge, a positive charge, and cationic amphiphilic drug, respectively. Lipids with pink head groups and dark blue head groups denote zwitterionic and anionic phospholipids, respectively. Panels A, B, and C denote the effects of pH, ion strength, and CADs, respectively.
