. 2009 Oct;50(10):2095–2102. doi: 10.1194/jlr.M900236-JLR200

TABLE 2.

Expression of Alzheimer's disease-related genes in primary human astrocytes and SKN-SH cells at baseline and following 48-h incubation in serum-free media

	Astrocytes		SK-N-SH
Gene	Baseline	48-h Incubation	Baseline	48-h Incubation
ABCA1	3.77 ± 0.3	1.43 ± 0.4^a	0.51 ± 0.1	1.42 ± 0.2^a
PLTP	2.46 ± 0.3	1.08 ± 0.3^a	0.84 ± 0.1	1.15 ± 0.3^a
APOE	0.86 ± 0.1	0.94 ± 0.2	NA	NA
MAPT	0.65 ± 0.2	1.18 ± 0.2^a	0.75 ± 0.1	1.16 ± 0.4^a
CDK5	0.26 ± 0.0	0.97 ± 0.3^a	0.90 ± 0.1	0.91 ± 0.2
GSK3β	1.08 ± 0.1	0.93 ± 0.1^a	0.88 ± 0.1	1.01 ± 0.2^a
APP	2.21 ± 0.2	1.01 ± 0.2^a	0.75 ± 0.1	0.96 ± 0.2^a
DAB1	6.90 ± 0.6	0.88 ± 0.2^a	0.13 ± 0.0	0.74 ± 0.1^a

Baseline levels in primary human astrocytes were measured in samples obtained from two donors, while 48-h incubation data were obtained from samples obtained from four donors. Data are shown as mean ± SD of gene/18S. NA, not applicable.

P ≤ 0.01 by t-test.