Fig. 2.

A rapidly adapting receptor (RAR) in response to injection of lidocaine (4 mg/kg) into the right ventricle (top 3 traces, R) and left ventricle (bottom 3 traces, L). Arrows indicate beginning and end of injection. RAR discharge ceased immediately following injection. Blockade of activity preceded the decrease in blood pressure. RAR was also inhibited by left-side injection with a much longer delay. The inhibition occurred after peak response in blood pressure. This suggests that the blockade is at the level of pulmonary circulation.