Fig. 6.
A: plasma concentrations of ACTH1-39 in LTH and control fetal sheep during infusion of AVP. AVP infusion was initiated immediately after the preinfusion sample (n = 4 per group; means ± SE). Concentrations of ACTH1-39 were significantly elevated (P < 0.05) in response to AVP in both groups. ACTH1-39 was significantly higher (P < 0.05) in LTH compared with control fetuses prior to and at the 15, 30, and 60 min times during AVP infusion. B: sum of fetal plasma ACTH1-39 for LTH and control fetuses from 0 (pre-AVP) through 90 min of AP infusion. AVP elicited a significantly higher total ACTH1-39 release in LTH compared with control fetuses over the sampling period (P < 0.05).