Table 1.

Analysis of tissue changes with chronic pressure overload

	Sham	PO
Age at termination, wk	18.4±1.6	18.8±1.7
Postsurgical recovery period, wk	9.4±1.6	9.8±1.8
% Heart weight	0.66±0.09	0.90±0.21*
% Wet lung weight	0.51±0.05	0.78±0.21*
% Dry lung weight	0.09±0.01	0.16±0.06*
LV volume, cm3	1.01±0.16	1.41±0.30*
RV volume, cm3	0.19±0.06	0.25±0.16
N	9	13

Values are expressed as means ± SD. PO, pressure overload; LV, left ventricle; RV, right ventricle.

^*P < 0.003 vs. Sham.