Fig. 5.

Direct infusion of bilirubin attenuates angiotensin II-induced hypertension. Mice were infused with 37.2 mg·kg⁻¹·day⁻¹ bilirubin for 5 days before the implantation of minipumps that delivered ANG II at 1 μg·kg⁻¹·min⁻¹. Blood pressure was measured in conscious freely moving mice by fluid-filled catheters for three consecutive days beginning 7 days after minipump implantation; n = 6. *P < 0.05 vs. ANG II.