Table 5.
Effect of intralipid on glycine kinetics
|
Ra, μmol·kg−1·h−1 |
Ra, mmol/h
|
Glycine Oxidation, %
|
Rate of Glycine Oxidation, μmol·kg−1·h−1
|
|||||
|---|---|---|---|---|---|---|---|---|
| Fast | IL | Fast | IL | Fast | IL | Fast | IL | |
| Control (n = 8) | 133.1±33.0 | 125.2±32.5* | 10.7±2.1 | 9.8±1.9* | 20.4±5.6 | 22.0±2.5 | 26.4±6.3 | 27.1±5.6 |
| NASH (n = 6) | 103.5±10.7† | 93.7±6.7 | 9.9±1.9 | 9.0±1.6* | 24.3±2.7 | 27.2±2.7 | 26.8±1.8 | 28.3±5.0 |
All data are means ± SD. IL = during intralipid infusion (440–480 min).
*
P < 0.01 compared with fast, paired t-test;
†
P < 0.05 compared with controls.