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Dox-induced damage results in changes in CD45(−) side population (SP). Flow cytometry was used to evaluate changes in the percentage of CD45(−) SP cells 24, 72, and 168 h following Dox treatment. Data were normalized to zero-time control animals and are presented as means ± SE (n = 5). *Statistical significance compared with zero-time control (P < 0.05). ‡Statistical significance compared with all other time points (P < 0.05).
