Table 3. Meta-analysis of direct comparisons and adjusted indirect comparisons of misoprostol, another uterotonic or placebo for risk of PPH.

PPH (≥ 1000 ml of blood)	RR	95% CI
Direct comparison, M, 600 µg vs 400 µg	0.841	0.501–1.411
Indirect adjusted comparison, M, 600 µg or 400 µg, vs P	1.420	0.790–2.555
Indirect adjusted comparison, M, 600 µg or 400 µg, vs U	0.931	0.599–1.446
All	1.023	0.707–1.481

CI, confidence interval; M, misoprostol; P, placebo; PPH, postpartum haemorrhage; RR, relative risk; U, uterotonic besides misoprostol.