Skip to main content
. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: J Immunol. 2009 Mar 1;182(5):3131–3138. doi: 10.4049/jimmunol.0803637

FIGURE 1. Spontaneous development of colonic inflammation in p50 KI mice.

FIGURE 1

A, Picture to compare the colons of WT and p105−/− mice, showing the loss of fecal matters and reduced length of the p105−/− colon. Data are representative of multiple mice. B, Hematoxylin-eosin staining of tissue sections of the distal portion of the colon from 8 week old control WT and p105−/− mice. An inflammatory cell follicle in the colonic mucosa (colonic patch) is indicated by an arrowhead. Original magnification, x20 and x40. C, Histological scores of mucosal inflammation in WT and p105−/− mice. Data were from three wildtype and three p105−/− mice (8 week of age), each with two colon sections. D, Real-time PCR showing the constitutive expression of several proinflammatory genes in the colon of p105−/− mice but not the WT mice.

HHS Vulnerability Disclosure