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. Author manuscript; available in PMC: 2009 Sep 9.
Published in final edited form as: Mol Ther. 2007 Oct 9;16(1):163–169. doi: 10.1038/sj.mt.6300323

Figure 7. Serum cytokine analysis.

Figure 7

Serum cytokine levels in the (a) athymic nude mice and (b) C57BL/6 mice 2 hours after the injection of different formulations at the dose of 1.2 mg siRNA/kg (2.4 mg DNA/kg for group F). A, phosphate-buffered saline (PBS); B, epidermal growth factor receptor (EGFR) small interfering RNA (siRNA) in PBS; C, EGFR siRNA and calf thymus DNA in non-targeted nanoparticle (NP); D, EGFR siRNA and calf thymus DNA in targeted NP; E, MDM2 siRNA and calf thymus DNA in targeted NP; F, calf thymus DNA in targeted NP (empty NP); G, EGFR siRNA and plasmid DNA in targeted NP. Data = mean ± SD, n = 3–8.