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. Author manuscript; available in PMC: 2009 Nov 15.
Published in final edited form as: J Cell Sci. 2008 Oct 28;121(Pt 22):3794–3802. doi: 10.1242/jcs.029678

Fig. 3.

Fig. 3

In vitro striation of cardiomyocytes. (A) Purified cardiomyocytes from 10-day-old embryonic myocardium were plated onto substrates of varying elasticity to observe striated cytoskeletal organization with skeletal α-actinin. Many cells on both soft gels and intermediate E* gels reassembled myofibrils whereas cells on hard matrices exhibited less myofibril reassembly. Inset images show magnified views of the larger images. (B) Fraction of cardiomyocytes that exhibit striation throughout the cytoplasm (± s.d. for >15 cells in triplicate studies). Organization appeared greatest on E* gels.