Table 1.
Demography and Severity Characteristics in BP-I Versus TC Subjects
| BP-I (n = 21) |
TC (n = 26) |
|||||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | t | p | |
| Age at MRI Scan (yrs) | 14.1 | 3.1 | 13.8 | 3.1 | .3 | NS |
| Age at Baseline (yrs) | 11.3 | 3.2 | 11.3 | 2.8 | .1 | NS |
| Age of Mania Onset (yrs) | 8.8 | 4.2 | — | — | — | — |
| Duration of Baseline Mania Episode (yrs) |
2.5 | 1.8 | — | — | — | — |
| CGAS at MRI Scan | 56.8 | 17.5 | 88.9 | 8.9 | 7.7 | <.001a |
| % | n | % | n | χ2 | p | |
| Sex | ||||||
| Male | 52.4 | 11 | 65.4 | 17 | .8 | NS |
| Female | 47.6 | 10 | 34.6 | 9 | ||
| Handedness | ||||||
| Right | 81.0 | 17 | 76.9 | 20 | F.E. | NS |
| Left | 19.0 | 4 | 23.1 | 6 | ||
| Race | ||||||
| Caucasian | 81.0 | 17 | 92.4 | 24 | 1.3 | NS |
| African-American | 9.5 | 2 | 3.8 | 1 | ||
| Other | 9.5 | 2 | 3.8 | 1 | ||
BP-I, bipolar I disorder; TC, typically developing control; MRI, magnetic resonance imaging; CGAS, Children’s Global Assessment Scale; F.E., Fisher’s Exact test.
a
Severity was included as a covariate in analyses comparing BP-I and TC groups.