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. Author manuscript; available in PMC: 2009 Sep 9.
Published in final edited form as: Mol Cell Biochem. 2009 Feb 18;328(1-2):9–16. doi: 10.1007/s11010-009-0067-8

Fig. 3.

Fig. 3

Model for translation regulation of NF-κB activation. The eIF2 kinases phosphorylate the α subunit of eIF2, which results in the translation inhibition of IκB synthesis. The reduction of IκB leads to the dissociation of IκB-NF-κB complex and subsequent NF-κB activation. The molecular network was depicted with CellDesigner® diagram editor