Table 1.
Differentially expressed proteins in hypothalamus from control and microgravity simulated mice
| Spot # | Protein name | Accession # | Peptide sequence | MOWSe score | Predicted molecular weight (Dalton) |
|---|---|---|---|---|---|
| Control | |||||
| 1 | Glutathione S-transferase | giI6754084 | RPWFAGDK | 107 | 25953 |
| 2 | Superoxide dismutase-2, mitochondrial | giI31980762 | RDFGSFEK | 117 | 24588 |
| Microgravity | |||||
| 3 | Malate dehydrogenase 1, NAD (soluble) | giI37589957 | GEFITTVQQR | 72 | 36488 |
| 4 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase alpha activation protein | giI 31981925 | NLLSVAYK | 92 | 29170 |
| 5 | Ubiquitin carboxy-terminal hydrolase L1 | giI 6755929 | EFTEREQGEVR | 69 | 24822 |
| 6 | Peroxiredoxin 6 | giI30267702 | LAPEFAKR | 86 | 24855 |
| 7 | Unnamed protein product | giI12852348 | EGVLYVGSK | 108 | 12425 |
Sequences obtained from MALDI-TOF-MS spectra are shown with their corresponding MOWSE score. Proteins identified in control and simulated microgravity of mice hippocampus are shown separately. The accession numbers indicated are from National Center for Biotechnology Information (NCBI)