TABLE 1.
S6clone | Mutation in Rpt1 | Mutation in Rpt2 | Interaction with INI1a | Interaction with INa |
---|---|---|---|---|
% | % | |||
S6 | 100 | 100 | ||
DD1 | F233L | 33 | <1 | |
DD2 | F204S | 33 | <1 | |
DD3 | V234A,I237T | 27 | <1 | |
DD4 | I195T,W206R | 28 | <1 | |
DD5 | I263T | <5 | 10 | |
DD6 | I264T,I268T | <1 | 10 |
a Percentage of β-galactosidase activity representing the interaction of wild type S6 protein with wild type INI1 or IN.