Table 2.

CRP group and cognitive outcomes

	CRP Groups
Variable	Undetectable < 0.5 mg/dL	Detectable 0.5 – 0.7 mg/dL	Elevated ≥0.8 mg/dL	p-value
MMSE score (mean ± SD)	25.1 ± 4.9	24.0 ± 5.2	22.5 ± 7.5	0.01*
Distribution of MMSE scores, N (%)
Score 28 – 30	35 (38)	28 (23)	28 (30)	0.09
Score 25 – 27	27 (30)	43 (36)	23 (24)
Score 14 – 24	25 (27)	41 (35)	30 (32)
Score < 13	4 (4)	7 (6)	11 (12)
Missing data†	1 (1)	0 (0)	2 (2)
Distribution of CDR scores, N (%)
Score = 0	50 (54)	56 (47)	39 (42)	0.02*
Score = 0.5	34 (38)	40 (34)	30 (33)
Score = 1	2 (2)	13 (11)	6 (6)
Score = 2	4 (4)	6 (5)	9 (10)
Score = 3	1 (1)	3 (2)	8 (9)
Missing data†	1 (1)	1 (1)	2 (2)
Frequency of cognitive diagnosis, N (%)
Nondemented	44 (48)	50 (42)	36 (38)	0.004*
CIND	38 (41)	39 (33)	25 (27)
Demented	10 (11)	30 (25)	33 (35)
Dementia etiology, N (%)
AD	9 (90)	21 (70)	22 (67)	0.41
VD or AD + VD	0 (0)	8 (27)	9 (27)
Other	1 (10)	1 (3)	2 (6)

^*p < 0.05

^†not included in Chi-square analysis

CRP = C-reactive protein; SD = standard deviation; MMSE = Mini-Mental Status Exam; CDR = Clinical Dementia Rating; CIND = Cognitive Impairment Not Demented; AD = Alzheimer’s Disease; VD = Vascular Dementia