. Author manuscript; available in PMC: 2010 May 13.

Published in final edited form as: J Am Chem Soc. 2009 May 13;131(18):6516–6524. doi: 10.1021/ja900147s

Table 3.

Stereoselective Synthesis of Trisubstituted α-Hydroxycyclopropyl Carbinols


entry	cyclopropyl boronate ester	α-hydroxy cyclopropyl carbinol	Isolated yield (%)^a
1			89^b
2			93^b
3			91
4			90
5			86
6			88
7			75^b
8			80

Only one diastereomer detected by ¹H NMR.

Syn stereochemistry of α-hydroxycyclopropyl carbinols established by single crystal X-ray diffraction.