Figure 4. Atg14 is not necessary to mediate the interaction of Vps15 and Gpa1.
Detergent-solubilized extracts from wildtype (WT) and atg14Δ mutant cells expressing the indicated Flag fusion proteins and Gpa1 fused to a Myc epitope were incubated with Flag resin, eluted with 3X Flag peptide, resolved by 10% SDS-PAGE, and analyzed by immunoblotting with antibodies against Flag, Myc, and G6PDH (Load control). IP, immunoprecipitation. WD, WD domain. KD, kinase domain. ID, intermediate domain. *, indicates protein of interest.