Table 7.
Factor | OR (95% CI) | p-value |
---|---|---|
Age | 1.01 (1.00–1.02) | 0.125 |
Male Sex | 2.1 (1.27–3.31) | 0.003 |
Injury Severity Score | 1.03 (1.00–1.05) | 0.027 |
Severe Thoracic Injury | 1.9 (1.17–3.04) | 0.009 |
Initial Base Deficit | 1.0 (1.03–1.15) | 0.002 |
Blood Transfusion (yes/no) | 5.5 (2.98–9.95) | < 0.001 |
History of diabetes mellitus | 2.9 (1.27–6.88) | 0.012 |
Variant T allele of TLR4 htSNP2 (rs1927911) | 6.1 (2.18–17.16) | 0.001 |
Variant T allele of TLR4 htSNP4 (rs2149356) | 0.2 (0.06–0.50) | 0.001 |
The data presented are the result of stepwise logistic regression analysis. Carriage of the TLR4 896 variant was no longer associated with complicated sepsis after adjusting for TLR4 htSNP2 and htSNP4.