Table 1.
MIC (mg/L) |
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---|---|---|---|---|---|---|
FTI |
tobramycin |
fosfomycin |
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Organism (no. of strains) | range | MIC50 (MIC90) | range | MIC50 (MIC90) | range | MIC50 (MIC90) |
S. aureusa (16) | 0.5–16 | 2 (8) | 0.125–512 | 0.5 (256) | 0.125–16 | 2 (4) |
S. pneumoniaea (8) | 4–32 | ND | 16–64 | ND | 8–32 | ND |
S. pyogenesb (5) | 16–32 | ND | 16–64 | ND | 16–64 | ND |
E. faecalisa (5) | 32 | ND | 8–512 | ND | 32 | ND |
E. colia (22) | 0.125–1 | 0.5 (1) | 0.5–1 | 1 (1) | 0.25–4 | 0.5 (2) |
H. influenzaea (16) | ≤0.13–4 | 0.5 (2) | 0.5–1 | 1 (1) | 0.25–4 | 0.5 (2) |
Klebsiella spp.b (22) | 0.5–16 | 1 (8) | 0.13–>512 | 0.13 (16) | 0.5–16 | 4 (16) |
M. catarrhalisa (5) | 0.5–1 | ND | 0.5–1 | ND | 4–16 | ND |
P. aeruginosaa, non-CF (60) | 1–256 | 4 (128) | 0.13–>512 | 1 (128) | 1–>512 | 32 (128) |
P. aeruginosaa, CF (100) | 1–128 | 8 (64) | 0.25–>512 | 2 (16) | 4–>512 | 64 (512) |
S. maltophiliaa (17) | 8–256 | 64 (128) | 2–>512 | 64 (256) | 32–512 | 64 (128) |
B. cepacia complexa (20) | 0.5–>512 | 512 (>512) | 1–>512 | 64 (512) | 512–>512 | >512 (>512) |
ND, not determined due to the small number of isolates examined.
aMICs were determined by the agar dilution method.
bMICs were determined by the broth microdilution method.