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. 2009 Aug 13;64(4):829–836. doi: 10.1093/jac/dkp282

Table 3.

PAE of FTI, tobramycin and fosfomycin for S. aureus P. aeruginosa and E. coli

Organism Antibiotic MIC (mg/L) PAE (h)
S. aureusa ATCC 29213 FTI 2.0 3.8
tobramycin 0.5 2.8
fosfomycin 2.0 1.3
P. aeruginosab ATCC 27853 FTI 4.0 3.0
tobramycin 0.5 2.0
fosfomycin 4.0 1.0
E. colib ATCC 25922 FTI 1.0 2.8
tobramycin 0.5 2.5
fosfomycin 2.0 1.0

aPAE was determined after a 2 h exposure to 2 × the MIC of antibiotic.

bPAE was determined after a 1 h exposure to 2 × the MIC of antibiotic.