Table 1.
Characteristics of the study population by kidney function and kidney damage, US men aged ≥ 20 years, NHANES III, 1988–1991†
| Kidney Dysfunction | Kidney Damage | ||||
|---|---|---|---|---|---|
| Overall | Normal eGFR ≥ 60 mL/min/1.73 m2 | Decreased eGFR < 60 mL/min/1.73 m2 | Elevated UACR ≥17 mg/g‡ | Normal UACR < 17 mg/g | |
| N | 1307 | 1224 | 83 | 189 | 1118 |
| Age, mean ± SE (years) | 41.9 ± 0.7 | 41.0 ± 0.7 | 69.7 ± 1.4 | 53.9 ± 2.9 | 40.6 ± 0.6 |
| Non-Hispanic White, % ± SE | 78.0 ± 3.3 | 77.9 ± 3.4 | 82.9 ± 3.1 | 72.7 ± 5.2 | 78.6 ± 3.3 |
| Blood Pressure, mean ± SE (mm Hg) | |||||
| Systolic | 124.4 ± 0.5 | 124.4 ± 0.4 | 127.1 ± 2.0 | 131.7 ± 1.4** | 123.7 ± 0.4 |
| Diastolic | 75.7 ± 0.5 | 75.8 ± 0.5 | 72.8 ± 1.8 | 76.4 ± 1.2 | 75.6 ± 0.5 |
| History of Hypertension, % ± SE | 28.9 ± 1.4 | 28.7 ± 1.5 | 42.2 ± 8.4 | 51.8 ± 4.7** | 26.5 ± 1.6 |
| Use of Antihypertensive Medications, % ± SE | 10.2 ± 1.0 | 9.4 ± 1.0 | 38.7 ± 6.4** | 20.5 ± 4.4* | 9.2 ± 1.0 |
| % Body Fat, mean ± SE | 24.9 ± 0.3 | 24.9 ± 0.3 | 24.6 ± 1.1 | 24.6 ± 0.8 | 25.0 ± 0.3 |
| History of Diabetes, % ± SE | 6.2 ± 0.8 | 6.2 ± 0.8 | 5.8 ± 5.5 | 21.1 ± 4.3** | 4.5 ± 0.7 |
| Current Smoker, % ± SE | 34.3 ± 2.2 | 34.9 ± 2.2 | 15.2 ± 4.6 | 30.0 ± 6.0 | 34.7 ± 2.3 |
*
p<0.05 compared to eGFR ≥ 60mL/min/1.73 m2
**
p<0.0001 compared to eGFR ≥ 60 mL/min/1.73 m2 or UACR <17 mg/g where appropriate
†
Estimates are weighted using the Phase I morning fasting sampling weights; All estimates by kidney dysfunction and damage besides age are age-adjusted
‡
UACR ≥ 17 mg/g is sex-specific cutoff for kidney damage in males