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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Stroke. 2008 Jul 31;39(10):2830–2836. doi: 10.1161/STROKEAHA.108.515684

Figure 2.

Figure 2

Immunostaining shows ICAM-1 immunoreactive vessels in the ischemic hemisphere from representative rats treated with rtPA alone (A through C) and S-0139 in combination with rtPA (D through F). C and F indicate the cortex. B and E represent the striatum. G, Quantitative data of ICAM-1 immunoreactive vessels (n=6 per group, # vs saline and * vs rtPA). Bar=25 µm (B to F). Monotherapy of rtPA was administered 4 hours after stroke, whereas combination therapy of S-0139 and rtPA was given 2 and 4 hours after stroke, respectively.