Table 1.

Binding Affinities of the Wild Type ING1-5 PHD Fingers for the Modified Histone H3 Tail Peptides

Protein	Peptide	Kd ± s.d. (μM)	Method	Reference
ING1	H3K4me3	3.3 ± 1.6	Fluorescence	Pena, P. et al., 2006
	H3K4me2	17.3 ± 3.9		Pena, P. et al., 2008
	H3K4me1	419 ± 71
ING2	H3K4me3	1.5 ± 1	Fluorescence	Pena, P. et al., 2006
	H3K4me2	15 ± 4
	H3K4me1	208 ± 80
ING3	H3K4me3	6.9 ± 1.1	Fluorescence	Pena, P. et al., 2006
ING4	H3K4me3 (12-mer)	7.9 ± 2	Fluorescence	Pena, P. et al., 2006
	H3K4me2	16.5 ± 1.1		Hung, T. et al., 2009
	H3K4me1	159 ± 20
	H3K4me0	205 ± 28
	H3K4me3 (15-mer)	4.0 ± 0.7	NMR	Palacios, A. et al., 2006
	H3K4me2	1.8 ± 1
	H3K4me1	1.6 ± 0.8
	H3K4me0	370 ± 20
	H3K4me3 (10-mer)	3.0 ± 0.6	NMR	Palacios, A. et al., 2008
	H3K4me2	9.2 ± 1.4
	H3K4me1	34 ± 4
	H3K4me0	274 ± 6
	H3R2me2/K4me3	19.2 ± 1.7
	H3K4me3 (10-mer)	6.4 ± 0.8	ITC	Palacios, A. et al., 2008
	H3K4me2	9.7 ± 0.6
	H3K4me1	45.8 ± 2.5
	H3K4me0	474 ± 67
ING5	H3K4me3	2.4 ± 1.0	Fluorescence	Pena, P. et al., 2006
	H3K4me2	16 ± 1.2		Champagne, K.S. et al., 2008
	H3K4me1	222 ± 17
	H3K4me0	261 ± 34