Table 2.

Binding Affinities of other Known H3K4me2/3-Recognizing PHD Fingers

Protein	Peptide	Kd ± s.d. (μM)	Method	Reference
BPTF	H3K4me3	2.7	ITC	Li, H. et al., 2006
	H3K4me2	5.0
Pygo	H3K4me3	2.5 ± 0.2	ITC	Fiedler, M. et al., 2008
	H3K4me2	2.4 ± 0.4
	H3K4me1	9.0 ± 0.4
	H3K4me0	no binding
	H3R2me2a/K4me2	2.1 ± 0.1
RAG2	H3K4me3	4	Fluorescence	Matthews, A.G.W. et al., 2007
	H3K4me2	60
	H3K4me1	120
	H3K4me0	500
	H3K4me3	33.8 ± 1.9	Fluorescence	Ramon-Maiques, S. et al.,2007
	H3K4me2	173.2 ± 25.1
	H3R2me2s/K4me3	25.1 ± 3.5
	H3R2me2a/K4me3	34.6 ± 5.0
TAF3	H3K4me3	0.16	Fluorescence	Vermeulen, M. et al., 2007
	H3K4me2	1.7
	H3K4me1	>200
	H3K4me0	>200
	H3K4me3	0.31 ± 0.09	Fluorescence	van Ingen, H., 2008
BHC80	H3K4me2	no binding	ITC	Lan, F. et al., 2007
	H3K4me1	459 105
	H3K4me0	33 6.4
DMNT3L	H3K4me3	>500	Fluorescence	Ooi, S.K.T. et al., 2007
	H3K4me2	>500
	H3K4me1	36.5 ± 3.5
	H3K4me0	2.1 ± 0.5
AIRE	H3K4me2	>500	Fluorescence	Org, T. et al., 2008
	H3K4me1	21.4 ± 5.9
	H3K4me0	4.7 ± 0.8
	H3K4me2	714 ± 90
	H3K4me1	55.6 ± 1.2	ITC	Org, T. et al., 2008
	H3K4me0	6.5 ± 0.2