Table 5.

Sensitivity ratios for the different lung regions (analysis of covariance model)^a

	PD15 (g/L)
Outcome measure	LS mean change from baseline	Standard error	Sensitivity indexb	F-testc	F-testd
Whole lung	-4.12	0.539	7.64	-	-
Basal region	-3.84	0.604	6.36	NS	-
Middle region	-3.82	0.673	5.68	NS	0.642
Apical region	-3.80	1.001	3.80	< 0.05	< 0.05

PD15, 15th percentile lung density; LS mean, least squares mean; NS, not significant.^aResults based on estimates for placebo group only. ^bRatio of absolute value of mean change divided by standard error. ^cRatio of outcome measure as compared to PD15 (whole lung). ^dRatio of outcome measure as compared to PD15 (basal region).