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. 2009 Aug 25;16(1):77. doi: 10.1186/1423-0127-16-77

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Copyright © 2009 Huang et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The effects of diabetes on I/R-induced ventricular rhythm disturbances including VPC (A), VT (B), and VF (C) were determined during ischemic period (1 h) in the age-matched controlled (n = 7), STZ-diabetic (n = 28), and insulin-treated diabetic (n = 9) rats. Data were expressed as means ± SEM, # P < 0.05 vs. DM. C, age-matched control; CS, control sham; DM, STZ-induced diabetes; DMS, DM sham; DMI, diabetes treated with insulin (4 IU/day for 5 days); DMIS, DMI sham; I/R, myocardial ischemia 1 h following by a 3 h of reperfusion; VPC, ventricular premature complexes; VT, ventricular tachycardia; VF, ventricular fibrillation.