. 2009 Sep 17;4(9):e7009. doi: 10.1371/journal.pone.0007009

Table 1. Inhibition constants (K _I ^*) of EgKU-8 acting on digestive serine proteases.

Target enzyme	K _I ^* (pM)^a
Bovine
Cationic trypsin	60±13
Chymotrypsin A	2050±170
Canine
Anionic trypsin	17±4
Cationic trypsin	22±8
Chymotrypsin B	NI^b

K _I ^*, the global equilibrium dissociation constants, were calculated from inhibition assays (see Figure 4A) according to equation 1 for tight-binding inhibitors and minimally corrected for the effect of substrate concentration according to equation 2. Values correspond to averages of independent measurements ± the standard error (n≥3).

NI, not inhibited.

Table 1. Inhibition constants (K I *) of EgKU-8 acting on digestive serine proteases.

Table 1. Inhibition constants (K _I ^*) of EgKU-8 acting on digestive serine proteases.