Table 2 Single‐nucleotide polymorphism alleles and haplotypes overtransmitted to patients with cleft lip with or without cleft palate from heterozygous parents.
| SNPs | T* | NT* | T† (%) | p Value‡ | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | ||||
| A | 116 | 84 | 58 | 0.014 | |||||||
| C | A | 64 | 38 | 63 | 0.014 | ||||||
| A | C | 80 | 48 | 63 | 0.015 | ||||||
| T | C | A | 36 | 19 | 65 | 0.023 | |||||
| C | A | C | 55 | 28 | 66 | 0.004 | |||||
| C | G | C | 39 | 20 | 66 | 0.017 | |||||
| T | C | A | C | 31 | 15 | 67 | 0.019 | ||||
| A | C | G | C | 39 | 16 | 71 | 0.003 | ||||
| T | C | A | C | G | 25 | 8 | 76 | 0.002 | |||
| C | A | C | A | T | 16 | 6 | 73 | 0.030 | |||
| C | A | C | G | C | 20 | 9 | 69 | 0.039 | |||
NT, non‐transmitted; SNP, single‐nucleotide polymorphism; T, transmitted.
*Counts of T and NT haplotypes from heterozygous parents.
†Transmission percentage.
‡ p Value for transmission disequilibrium test.