(a) Structures of chavicol, anol, eugenol, isoeugenol, and their methylated derivatives. The carbon numbering system used in the text is shown.
(b) The reaction mechanism of EGS and IGS uses a quinone methide intermediate (Louie et al., 2007). B (in blue) represents a general base consisting of K132 and a bridging water molecule. H- (in red) represents the hydride transferred from NADPH.