Table 4. Relative risks (RRs) of melanoma by daily servings of fruits and vegetables and by frequency of consumption of orange juice.
Cases | Person-years (thousands) | Multivariateb RR (95% CIc) | |
---|---|---|---|
Total fruits | |||
<1.0 | 62 | 349 | 1.00 |
1.0–1.4 | 58 | 274 | 1.16 (0.80–1.66) |
1.5–2.4 | 151 | 524 | 1.42 (0.99–2.04) |
2.5–3.4 | 83 | 303 | 1.37 (0.95–1.98) |
⩾3.5 | 60 | 198 | 1.37 (0.86–2.20) |
P for linear trend | 0.22 | ||
Total vegetables | |||
<2.0 | 86 | 448 | 1.00 |
2.0–2.9 | 126 | 479 | 1.22 (0.92–1.62) |
3.0–3.9 | 106 | 356 | 1.32 (0.97–1.78) |
4.0–4.9 | 53 | 196 | 1.11 (0.76–1.62) |
⩾5.0 | 43 | 169 | 1.01 (0.68–1.50) |
P for linear trend | 0.81 | ||
Fruits and vegetables high in carotenoids | |||
<0.25 | 50 | 263 | 1.00 |
0.25–0.49 | 116 | 447 | 1.30 (0.51–3.33)* |
0.50–0.74 | 85 | 347 | 1.18 (0.49–2.85)* |
0.75–0.99 | 68 | 236 | 1.40 (0.73–2.68) |
⩾1.00 | 95 | 355 | 1.24 (0.67–2.29) |
P for linear trend | 0.78 | ||
Fruits and vegetables high in vitamin C | |||
<0.5 | 57 | 317 | 1.00 |
0.5–0.9 | 77 | 376 | 1.10 (0.77–1.55) |
1.0–1.4 | 96 | 378 | 1.33 (0.94–1.87) |
1.5–1.9 | 92 | 280 | 1.54 (1.06–2.22) |
⩾2.0 | 92 | 297 | 1.43 (0.99–2.07) |
P for linear trend | 0.01 | ||
Orange juiced | |||
Never | 39 | 228 | 1.00 |
1–3 month−1 | 70 | 364 | 1.09 (0.73–1.62) |
1 week−1 | 44 | 197 | 1.31 (0.83–2.05) |
2–6 week−1 | 203 | 799 | 1.44 (1.00–2.08) |
⩾1 day−1 | 147 | 499 | 1.61 (0.92–2.84) |
P for linear trend | 0.008 |
P<0.05 in test for heterogeneity of results from the NHS and NHS II.
Results from NHS (1984–1998) and NHS II (1991–1999) were pooled to obtain risk estimates for the combined cohorts.
Relative risks were adjusted for the covariates listed in Table 2 footnote c plus total energy intake, multivitamin use, and use of vitamin C, vitamin E, and β-carotene supplements.
95% confidence interval.
Follow-up for NHS is 1980 – 1998.