Table 1. Protein expression of cyclin D1, D3, E, and p27 evaluated by TMA, graded into four groups from negative (1) to positive (4).
Conventional | Papillary | Chromophobe | |||||
---|---|---|---|---|---|---|---|
Cyclin D1 | |||||||
1 | Low | 64 | 47% | 21 | 90% | 11 | 79% |
2 | 18 | 5 | 0 | ||||
3 | High | 30 | 53% | 2 | 10% | 1 | 21% |
4 | 62 | 1 | 2 | ||||
Cyclin D3 | |||||||
1 | Low | 108 | 83% | 21 | 90% | 10 | 86% |
2 | 33 | 5 | 2 | ||||
3 | High | 17 | 17% | 1 | 10% | 1 | 14% |
4 | 12 | 2 | 1 | ||||
Cyclin E | |||||||
1 | Low | 72 | 68% | 9 | 67% | 5 | 46% |
2 | 47 | 9 | 1 | ||||
3 | High | 41 | 32% | 7 | 33% | 2 | 54% |
4 | 14 | 2 | 5 | ||||
p27 | |||||||
1 | Low | 16 | 20% | 6 | 34% | 8 | 64% |
2 | 19 | 4 | 1 | ||||
3 | High | 115 | 80% | 18 | 66% | 5 | 36% |
4 | 21 | 1 | 0 |
Numbers of cases in each group are noted