Table 2. Mutations in the ST7 gene.
| Case | Type of tumour | Locations | Mutations | Amino-acid substitution | Status | Microsatellite instability |
|---|---|---|---|---|---|---|
| CRC39 | Colorectal | Intron 8 (−32 nt from exon 9) | 1 to 3 nt deletion (heterogeneous) | None | Somatic mutation | MSI-H |
| GC18 | Gastric | Intron 8 (−32 nt from exon 9) | 1 to 3 nt deletion (heterogeneous) | None | Somatic mutation | MSI-H |
| GC28 | Gastric | Intron 8 (−32 nt from exon 9) | 1 to 3 nt deletion (heterogeneous) | None | Somatic mutation | MSI-H |
| CRC18 | Colorectal | Exon 5 | 427 G to A (heterozygous) | 143 Ala to Thr | Germline mutation or rare polymorphism | MSS |
nt=nucleotide; CRC=colorectal cancer; GC=gastric cancer; MSI-H=microsatellite instability-high; MSS=microsatellite stable.