Table 3. Polymorphisms in the ST7 gene locus detected in this study.
Allele frequency |
||||
---|---|---|---|---|
Location | Nt | CRC | GC | HCC |
Intron 8 (−31 nt from exon 9) | A/T | 0.05/0.95 | 0.02/0.98 | 0.03/0.97 |
Intron 10 (+8 nt from exon 9) | T/C | 0.20/0.80 | 0.20/0.80 | 0.18/0.82 |
Intron 11 (+17 nt from exon 10) | C/T | 0.20/0.80 | 0.20/0.80 | 0.16/0.84 |
Intron 15 (+28 nt from exon 14) | T/G | 0.00/1.00 | 0.01/0.99 | 0.00/1.00 |
nt=nucleotide; CRC=colorectal cancer; GC=gastric cancer; HCC=hepatocellular carcinoma. Allele frequency was determined in each of the 48 cancers.