Table 2. Summary of microarray results.
ID number | ID name | Common name | Functiona | Ratiob |
---|---|---|---|---|
724588 | ISGF3G | Interferon-stimulated transcription factor 3 gamma, p48, IRF-9 | Responsible for the initial stimulation of IFN-α- and β-responsive genes, it recognises and binds to the IFN-stimulated response element, or ISRE within the regulatory sequences of target genes. ISGF3 plays a primary role in the transmission of a signal from the cell surface to the nucleus | 9 |
796542 | ETV5 | ERM, ETS-related protein | Binds to DNA sequences containing the consensus nucleotide core sequence ggaa | 6 |
50794 | ZNF133 | Zinc-finger protein 133 | May be involved in transcriptional regulation as a repressor | 4 |
455121 | CEBPG | CCAAT/enhancer binding protein gamma | Transcription factor that binds to the enhancer element PRE-i (positive regulatory element-i) of the IL-4 gene. Might change the DNA-binding specificity of other transcription factors and recruit them to unusual DNA sites | 4 |
Description of genes are modified from Rebhan et al. (1997). URL: http://bioinformatics.weizmann.ac.il/cards.
OHS and II-11b cells treated with IFN-γ (10 U ml−1, 48 h) vs untreated control, average ratio from four hybridisations.