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Electron micrographs of control (a) and diabetic (b) parotid gland acinar cells. Control acinar cells show basally located nuclei (N) and abundant rough ER (rER), and numerous, dense, apically located secretory granules. Cells of diabetic animals contain secretory granules of variable density, basally located lipid droplets (LD), occasional crystalloid lysosomes (arrows) and autophagic vacuoles (AV). Lu, lumen; IC, intercellular canaliculus; MEC, myoepithelial cell. Scale bars = 2 μm.
