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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Laryngoscope. 2008 Oct;118(10):1793–1800. doi: 10.1097/MLG.0b013e31817d01cd

Figure 1.

Figure 1

Processes involved in gentamicin distribution in the inner ear (adapted from Plontke et al.6. They include 1) Clearance from the middle ear (ME); 2) Permeability of the round window (RW) membrane; 3) Clearance from scala tympani (ST) to blood; 4) Clearance from scala vestibuli (SV) to blood; 5) Diffusion along the scalae; 6) ST-SV communication through the helicotrema; 7) Inter scala communications (ST-endolymphatic space (ELS), SV-ELS, ST-SV); 8) Clearance from the vestibule (Vest) to blood.