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Increased cardiac glucose uptake in WT FVB mice in response to exogenous insulin and leptin administration is dependent on SGLT1. (A) Increased glucose uptake observed after insulin administration was inhibited by phlorizin, a SGLT1 inhibitor. (B) Increased glucose uptake observed after leptin administration was completely inhibited by phlorizin (n = 3 per group). Data are expressed as mean ± SE. *P < 0.05; †P < 0.01; NS, not significant.
