Table 2.
VEEV neutralizing antibody levels for pre-challenge sera samples in T cell transfer trial 4
Group description | PRNT50 (Day -1) |
||||
---|---|---|---|---|---|
Recipient strain | T cell donor strain | No. positive/total tested | Percent positive (titer≥20) |
Titer range | Geometric mean titer |
αβ TCR KO | WT | 12/15 | 80% | 20 – 160 | 17 |
αβ TCR KO | None | 0/9 | 0% | - | 1 |
VEEV-specific antibody response was assessed by PRNT of individual sera samples in T Cell Transfer Trial 4 (described in Fig. 2D) obtained 24 hours (day -1) prior to VEEV challenge. The titer is reported as the reciprocal of the serum dilution corresponding to an endpoint of 50% plaque reduction. For PRNT values that were below the limit of detection (<20), an arbitrary value of 1 was used for calculation of the geometric mean titer, presented by group. a(), procedure to be performed; bN.D., not done.