Table 1.
Characteristics of the study population*
| Characteristic | Entire cohort (n=899) |
|---|---|
| Age, years | 56±14 |
| Male gender | 612 (68) |
| Race | |
| Caucasian | 725 (81) |
| African American | 127 (14) |
| Other | 32 (4) |
| Tobacco use | |
| Never | 348 (39) |
| Former | 492 (55) |
| Current | 59 (6) |
| Hypertension | 320 (36) |
| Diabetes mellitus | 209 (23) |
| Serum creatinine, mg/dL | 1.3±0.7 |
| Body mass index, kg/m2 | 29±6.6 |
| Systolic blood pressure, mmHg | 113±18 |
| Cardiomyopathy etiology | |
| Ischemic | 293 (33) |
| Nonischemic | 606 (67) |
| NYHA Class | |
| I | 134 (15) |
| II | 388 (43) |
| III | 267 (30) |
| IV | 110 (12) |
| Ejection Fraction, percent | 32±17 |
| Bundle Branch Block | |
| Neither | 742 (82) |
| Left BBB | 98 (11) |
| Right BBB | 59 (7) |
| Atrial Fibrillation/Flutter | 307 (35) |
| Ventricular Tachycardia | 254 (28) |
| Cardiac resynchronization | 249 (28) |
| Ace-inhibitor or ARB | 768 (85) |
| Beta blocker | 749 (83) |
| Digoxin | 417 (46) |
| Diuretic | 637 (71) |
| Serum NRG-1β, ng/ml | |
| Median (IQR) | 5.2 (3.4, 8.6) |
| Mean±sd | 7.0±5.9 |
| Plasma BNP, pg/ml (n=744) | |
| Median (IQR) | 120 (35, 384) |
| Mean±sd | 322±507 |
*
Data are displayed as mean±sd or frequency (percent), unless otherwise indicated