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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Diagn Microbiol Infect Dis. 2009 Apr 2;64(2):229–232. doi: 10.1016/j.diagmicrobio.2009.02.001

Fig. 2.

Fig. 2

Detection of γdPGA by quantitative antigen capture ELISA (X-axis) and by latex agglutination (Y-axis) in serum from murine (●) and non-human primate (○) models of pulmonary anthrax. Mice and cynomolgus monkeys were challenged by the pulmonary route with lethal doses of B. anthracis spores. Blood was collected at various times after challenge and assayed for γdPGA. Each data point represents a single serum sample that was analyzed by both the ELISA (PGA concentration) and by latex agglutination (Agglutination score). Results from the latex agglutination immunoassay of undiluted sera are reported as the agglutination score as described in Fig. 1A. Two agglutination reactions are shown that correspond to the samples labeled A and B.